diff --git a/substrate/Cargo.lock b/substrate/Cargo.lock
index b9d4696b20..f400554404 100644
--- a/substrate/Cargo.lock
+++ b/substrate/Cargo.lock
@@ -1799,7 +1799,6 @@ dependencies = [
  "rustc-hex 1.0.0 (registry+https://github.com/rust-lang/crates.io-index)",
  "safe-mix 1.0.0 (registry+https://github.com/rust-lang/crates.io-index)",
  "serde 1.0.80 (registry+https://github.com/rust-lang/crates.io-index)",
- "serde_derive 1.0.80 (registry+https://github.com/rust-lang/crates.io-index)",
  "sr-primitives 0.1.0",
  "sr-std 0.1.0",
  "sr-version 0.1.0",
diff --git a/substrate/node/runtime/Cargo.toml b/substrate/node/runtime/Cargo.toml
index 6ca724a81b..774513d76b 100644
--- a/substrate/node/runtime/Cargo.toml
+++ b/substrate/node/runtime/Cargo.toml
@@ -7,7 +7,6 @@ authors = ["Parity Technologies <admin@parity.io>"]
 rustc-hex = "1.0"
 hex-literal = "0.1.0"
 serde = { version = "1.0", default-features = false }
-serde_derive = { version = "1.0", optional = true }
 safe-mix = { version = "1.0", default-features = false }
 parity-codec = "2.1"
 parity-codec-derive = "2.1"
@@ -57,7 +56,6 @@ std = [
 	"srml-upgrade-key/std",
 	"sr-version/std",
 	"node-primitives/std",
-	"serde_derive",
 	"serde/std",
 	"safe-mix/std",
 	"substrate-client/std",
diff --git a/substrate/node/runtime/src/lib.rs b/substrate/node/runtime/src/lib.rs
index f3d1672642..a5f1fd96f7 100644
--- a/substrate/node/runtime/src/lib.rs
+++ b/substrate/node/runtime/src/lib.rs
@@ -26,10 +26,6 @@ extern crate srml_support;
 #[macro_use]
 extern crate sr_primitives as runtime_primitives;
 
-#[cfg(feature = "std")]
-#[macro_use]
-extern crate serde_derive;
-
 extern crate substrate_primitives;
 
 #[macro_use]